NFL Week 5 Odds & Betting Lines (Spread, Total, Moneyline)

Companies featured on this page may be our partners that compensate us if you sign up for one through our links. This doesn't affect our ratings or opinions in any way. Learn more here. Must be 21+. Gambling Problem? Call 1-800-GAMBLER.

Use our free NFL Week 5 odds comparison tool below to shop for the best spread, total, and moneyline odds and lines at legal online sportsbooks in the U.S. Filter by state and sportsbooks to see only the ones you want.

Once you find the best odds or lines for Week 5, simply click the tile to sign up (if you aren't already a user) and place your bet.

Scroll to the right to compare current NFL odds & lines at sportsbooks >>

Spread
Moneyline
Total
Default

Oct 05 CHI @ WAS

08:15 PM

Chicago

Bears

Washington

Commanders

Oct 05 CHI @ WAS

08:15 PM

Chicago

Bears

Washington

Commanders

Oct 05 CHI @ WAS

08:15 PM

Chicago

Bears

Washington

Commanders

Oct 08 BUF @ JAX

09:30 AM

Buffalo

Bills

Jacksonville

Jaguars

Oct 08 BUF @ JAX

09:30 AM

Buffalo

Bills

Jacksonville

Jaguars

Oct 08 BUF @ JAX

09:30 AM

Buffalo

Bills

Jacksonville

Jaguars

Oct 08 NO @ NE

01:00 PM

New Orleans

Saints

New England

Patriots

Oct 08 NO @ NE

01:00 PM

New Orleans

Saints

New England

Patriots

Oct 08 NO @ NE

01:00 PM

New Orleans

Saints

New England

Patriots

Oct 08 ATL @ HOU

01:00 PM

Atlanta

Falcons

Houston

Texans

Oct 08 ATL @ HOU

01:00 PM

Atlanta

Falcons

Houston

Texans

Oct 08 ATL @ HOU

01:00 PM

Atlanta

Falcons

Houston

Texans

Oct 08 NYG @ MIA

01:00 PM

New York

Giants

Miami

Dolphins

Oct 08 NYG @ MIA

01:00 PM

New York

Giants

Miami

Dolphins

Oct 08 NYG @ MIA

01:00 PM

New York

Giants

Miami

Dolphins

Oct 08 CAR @ DET

01:00 PM

Carolina

Panthers

Detroit

Lions

Oct 08 CAR @ DET

01:00 PM

Carolina

Panthers

Detroit

Lions

Oct 08 CAR @ DET

01:00 PM

Carolina

Panthers

Detroit

Lions

Oct 08 BAL @ PIT

01:00 PM

Baltimore

Ravens

Pittsburgh

Steelers

Oct 08 BAL @ PIT

01:00 PM

Baltimore

Ravens

Pittsburgh

Steelers

Oct 08 BAL @ PIT

01:00 PM

Baltimore

Ravens

Pittsburgh

Steelers

Oct 08 IND @ TEN

01:00 PM

Indianapolis

Colts

Tennessee

Titans

Oct 08 IND @ TEN

01:00 PM

Indianapolis

Colts

Tennessee

Titans

Oct 08 IND @ TEN

01:00 PM

Indianapolis

Colts

Tennessee

Titans

Oct 08 ARI @ CIN

04:05 PM

Arizona

Cardinals

Cincinnati

Bengals

Oct 08 ARI @ CIN

04:05 PM

Arizona

Cardinals

Cincinnati

Bengals

Oct 08 ARI @ CIN

04:05 PM

Arizona

Cardinals

Cincinnati

Bengals

Oct 08 LAR @ PHI

04:05 PM

Los Angeles

Rams

Philadelphia

Eagles

Oct 08 LAR @ PHI

04:05 PM

Los Angeles

Rams

Philadelphia

Eagles

Oct 08 LAR @ PHI

04:05 PM

Los Angeles

Rams

Philadelphia

Eagles

Oct 08 MIN @ KC

04:25 PM

Minnesota

Vikings

Kansas City

Chiefs

Oct 08 MIN @ KC

04:25 PM

Minnesota

Vikings

Kansas City

Chiefs

Oct 08 MIN @ KC

04:25 PM

Minnesota

Vikings

Kansas City

Chiefs

Oct 08 DEN @ NYJ

04:25 PM

Denver

Broncos

New York

Jets

Oct 08 DEN @ NYJ

04:25 PM

Denver

Broncos

New York

Jets

Oct 08 DEN @ NYJ

04:25 PM

Denver

Broncos

New York

Jets

Oct 08 DAL @ SF

08:20 PM

Dallas

Cowboys

San Francisco

49ers

Oct 08 DAL @ SF

08:20 PM

Dallas

Cowboys

San Francisco

49ers

Oct 08 DAL @ SF

08:20 PM

Dallas

Cowboys

San Francisco

49ers

Oct 09 GB @ LV

08:15 PM

Green Bay

Packers

Las Vegas

Raiders

Oct 09 GB @ LV

08:15 PM

Green Bay

Packers

Las Vegas

Raiders

Oct 09 GB @ LV

08:15 PM

Green Bay

Packers

Las Vegas

Raiders

Dave Rathmanner

Dave Rathmanner is the Founder & CEO of Odds Assist. After struggling to find helpful sports betting resources and honest reviews when he first started betting, he decided to create the site he always wished he had. Dave has been betting on sports since NJ legalized it in 2018 and regularly analyzes sportsbooks to find the best options for bettors. Aside from creating new content for OA readers, Dave is also passionate about researching betting markets, creating models, and developing profitable betting strategies.