Denver Broncos @ Los Angeles Chargers – Week 6 MNF Picks & Betting Preview

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For the first time in two years, the Denver Broncos will play in the final NFL game of the week, traveling to Los Angeles to face the Chargers on Monday Night Football.

The Broncos bring with them a lock-down defense to square off against an explosive Chargers offense.

In a battle of strength versus strength, will Denver’s defense or Los Angeles’ offense come out on top? Or will the Broncos’ maligned offense do enough to best the Chargers’ middle-tier defense?

Read on for three top picks from this upcoming AFC West matchup at SoFi Stadium.

  • Time: 8:15 pm ET
  • TV: ESPN
  • Location: SoFi Stadium in Inglewood, California
  • Weather: Dome, 67°, mostly clear

Pick 1: Los Angeles Chargers Moneyline

Since Chargers QB Justin Herbert joined the team in 2020, Los Angeles is 2-0 against the Broncos at home. While new Denver QB Russell Wilson adds a new dimension to this team, the results for the Broncos have been less than stellar.

Wilson is still on the mend from a shoulder injury, requiring an injection earlier this week to ease the pain. Although he’s expected to play, I think the Chargers will continue their winning streak at home against the Broncos.

Pick 2: Los Angeles Chargers –4.5

This is a tale of two teams heading in the opposite direction. Denver enters the game losers of two straight, falling last week on Thursday night to Indianapolis. Los Angeles has won two in a row, beating both Cleveland and Houston on the road.

Further, Denver is 1-4 ATS this year while Los Angeles is 4-1 ATS through five games. Both teams need a win to remain in the playoff chase this season.

Expect the Chargers to win by at least a TD to continue each team’s respective streak.

Pick 3: Justin Herbert Over 1.5 Passing TDs (-154 at FanDuel Sportsbook)

The Chargers QB has played Denver four times, completing 65% of his passes for eight TDs against the division-rival Broncos. Only once—in his first season—has Herbert failed to pass for two TDs against Denver.

Herbert is due for a big game. After tossing for six TDs and 611 yards against Kansas City and Las Vegas to begin the year, Herbert has tossed only four TDs in his previous three games.

Expect the sensational signal caller to break out against Denver and toss at least two TDs for Los Angeles.

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