New Orleans Saints @ Arizona Cardinals – Week 7 TNF Picks & Betting Preview

You are currently viewing New Orleans Saints @ Arizona Cardinals – Week 7 TNF Picks & Betting Preview

Some of the sportsbooks featured on this page are our partners. We may receive compensation if you sign up for one through our links, but this doesn't affect our ratings or opinions in any way. You can learn more by visiting our advertiser disclosure page.

Both the New Orleans Saints and Arizona Cardinals enter this crucial Thursday Night Football showdown with their backs against the wall. 

With identical 2-4 records and both teams coming off a loss last week, it’s almost safe to say this is a must-win game if either team hopes to have a shot at making the playoffs.

Here's our betting preview and picks for this Week 7 TNF matchup.

  • Time: Thursday, October 20, 2022, at 8:15 PM ET
  • TV: Amazon Prime
  • Game Location: State Farm Stadium in Glendale, AZ
  • Weather: Dome (the roof is not expected to be open)

Pick 1: UNDER 44 Points (-107 on PointsBet)

Thursday Night Football has been consistently producing games that go under the total with 5 of 6 Thursday games going under so far in 2022. That trend should continue Thursday night when two banged-up teams—especially offensively—square off.

The Saints will likely use Andy Dalton at QB again as Jameis Winston continues to deal with a back injury. They should get Chris Olave back at receiver from a concussion, but they will still be without other top receivers Jarvis Landry and Michael Thomas.

These injuries have forced the Saints to become a run-heavy team. They have rushed for over 200 yards in each of their last two games.

The Cardinals' offense, on the other hand, has been all out of sync and they may or may not have running back James Conner who will be a game-time decision with a rib injury.

The Cardinals have averaged under 17 points per game at home this year. The Cardinals have only gone over the total twice in their last 10 games, while 3 of the last 5 Saints’ road games have gone under.

Prop Bet 1: Alvin Kamara over 63.5 Rush Yards (-113 on BetMGM)

When Kamara has been healthy he has had success running the ball. In his last two games, he is averaging over 100 yards on the ground.

The Cardinals' run defense has been worse at home than on the road. They have allowed 122 rush yards per game at home compared to just 60 yards per game on the road.

Look for Kamara to get plenty of touches given the injuries in the Saints' passing game and get over 63.5 yards.

Prop Bet 2: Zach Ertz under 45.5 Receiving Yards (-120 on BetMGM)

The Saints have done a fantastic job against the tight end in the early part of the 2022 season. They have only allowed a tight end to go for more than 45 yards once on the season.

They have managed to shut down Irv Smith, Cameron Brate, Kyle Pitts, and Hayden Hurst, so it’s not like the Saints' defense has been going against bottom-level tight ends.

In three home games, Ertz has gone over 45 yards only once. Look for that trend to continue in this TNF matchup.

NFL Sign-Up Bonuses

*Special offers from our partners. May vary by state.

Our Partners

Intro Bonus

Next Steps

No Sweat First Bet Up to $1,000

States: AZ, CO, CT, IL, IN, IA, KS, LA, MD, MI, NJ, NY, PA, TN, WV, WY, VA

2 Second Chance Bets Up to $2,000

States: CO, IL, IN, IA, KS, MD, MI, NJ, NY, PA, WV, VA

Bet $10, Get $200 Free

States: AZ, CO, IL, IN, IA, KS, LA, MD, MI, NJ, TN, VA, WV, WY

Bet $100, Get $100 Free Bet

States: AZ, CO, IN, LA, MI, NJ, NY, TN, VA

Rob O'Connor

Rob O’Connor is a veteran sports handicapper. He broke into the industry in 2002 and has continued to provide his clients with high quality sports handicapping advice ever since. He is currently a handicapper with Rob Veno Sports and prior to that ran his own sports handicapping service. Rob has been featured on ESPN Radio as well as on his hometown sports station WIP out of Philadelphia. Rob O'Connor handicaps the NFL, College Football, College Basketball, and Major League Baseball.