NFL Week 15 Opening Line Betting Picks

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We went 1-1 on our NFL Week 14 opening line picks after the Steelers and Patriots surprisingly combined for 39 points on Thursday night.

As always, we've got two more opening NFL line picks to make now before the lines move—two spread bets for this week.

You can see all of our current and historical NFL picks in our Best NFL Bets & Picks Guide. You can also compare NFL lines and odds by sportsbooks here.

New Orleans Saints -4 vs New York Giants – 1 pm ET

The Giants picked up a 24-22 win over the Packers on Monday Night Football and now travel to New Orleans on a short week to take on the Saints who will be playing a third-consecutive home game following a 28-6 win over the Panthers last week. So in addition to being the better football team, it’s a great scheduling spot for the Saints.

Giants QB Tommy Devito has been a nice story, he has come out of nowhere to lead the Giants to 3 straight wins while throwing 5 touchdowns and 0 interceptions. However, now he is going to be facing a much tougher defense in the Saints.

The Saints rank 7th in the league against the pass giving up just 189.5 yards per game. And the Giants offense, despite the win streak, is still ranked 31st in the league, putting up only 267 yards per game.

The Giants defense is also not very good, ranking 26th, giving up 361.4 yards per game.

The Giants won’t be able to get enough stops and their offense won’t be able to score enough to keep up with QB Derek Carr and the Saints.

Look for the Saints to control this one on both sides of the ball and pick up the win and cover in a great spot on Sunday afternoon.


Buffalo Bills -2 vs Dallas Cowboys – 4:25 pm ET

The Bills saved their season last week with a hard-fought 20-17 victory over the Kansas Chiefs. Now they get a chance to build off that when the Cowboys come to town Sunday afternoon.

The Cowboys' 10-3 record is really not impressive at all when you look at who they have beaten. They have one win against a team with a winning record and that was last week over the Eagles in Dallas. The Cowboys' other 9 wins have come against teams with a combined record of 40-77.

Now they travel to Buffalo to play a cold-weather game against a team that is 5-1 at home on the season.

The Cowboys rank 4th in yards per game and the Bills are right behind them in 5th.

Defensively these teams are evenly matched too, with the Cowboys allowing 17.9 points and the Bills allowing 18.8 points per game. But the Bills are better defensively at home, where they are giving up just 14.5 points per game.

The Bills will look to keep the Dallas offense off the field by controlling time of possession. In their last 3 games, they have held the ball for over 36 minutes per game. That will give the Dallas offense fewer opportunities to score.

The Bills just held the Chiefs to 17 points and they held the Dolphins to 20 points earlier this year, so the defense clearly knows how to reign in a high-powered offense.

Getting the Bills at under a FG at home has some value and looks like the right side Sunday afternoon.


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Rob O'Connor

Rob O’Connor is a veteran sports handicapper. He broke into the industry in 2002 and has continued to provide his clients with high quality sports handicapping advice ever since. He is currently a handicapper with Rob Veno Sports and prior to that ran his own sports handicapping service. Rob has been featured on ESPN Radio as well as on his hometown sports station WIP out of Philadelphia. Rob O'Connor handicaps the NFL, College Football, College Basketball, and Major League Baseball.